YOUNG INVESTIGATOR – ACTIVE PROJECTS
Jamie Anastas, PhD
Baylor College of Medicine
Focus: Pediatric High-Grade Glioma
Project title: Combinatorial targeting of HDACs and LSD1 to treat pediatric brain tumors
Joanna Gell, MD
Connecticut Children’s
Focus: Intracranial Germ Cell Tumor (iGCT)
Project title: Development of a targeted compound for the germ cell tumor marker PRDM14
Francesca Nazio, PhD
Ospedale Pediatrico Bambino Gesù
Focus: Medulloblastoma
Project title: Targeting autophagy to boost the immune response against medulloblastoma
Estibaliz Lopez Rodrigo, MD
Memorial Sloan Kettering Cancer Center
Focus: Metastatic Osteosarcoma
Project title: Targeting macrophages in lung osteosarcomagenesis
Dr. Kathryn Lemberg
Johns Hopkins University
Focus: Malignant Peripheral Nerve Sheath Tumor
Project Title: JHU395: A glutamine antagonist for malignant peripheral nerve sheath tumor
Mark Kohler, MD, PhD
University of Colorado Cancer Center
Focus: Acute Myeloid Leukemia (AML)
Project title: Multi-antigen targeting CAR T cells for relapsed/refractory pediatric AML
Dr. Ranjith Menon Muraleedharan
Yale University School of Medicine
Focus: Diffuse Intrinsic Pontine Glioma
Project Title: Exploiting metabolic defects with NAMPT inhibitors in DIPG
Adam Durbin, MD, PhD
St. Jude Children’s Research Hospital
Focus: Neuroblastoma
Project title: Novel agents targeting EP300-regulated transcription in neuroblastoma
Dr. Loretta Li
Ann & Robert H. Lurie Children’s Hospital of Chicago & Northwestern University
Focus: High-risk B-cell Acute Lymphoblastic Leukemia
Project Title: JAK2 inhibition and degradation in B-cell acute lymphoblastic leukemia