CureSearch Impact Report
Summer 2014

MAGGIE
Leukemia, age 3

As we work to find cures and improve treatments for children with cancer, we are guided by our CureSearch core values:

HONESTY & INTEGRITY
TRANSPARENCY & ACCOUNTABILITY
CREATIVITY & COLLABORATION

At just 9 weeks old, Tate Hartzler was diagnosed with hepatoblastoma, a rare liver cancer affecting children. After undergoing 12 weeks of chemotherapy, radiation, and surgery, Tate completed treatment when he was only 8 months old. 25 years ago, the prognosis for Tate would have been grim. Today, Tate and his family have every reason to look forward to the future.

CureSearch
works daily for
children like Tate.

ADVANCING RESEARCH

After all, in the last 30 years, research has been responsible for saving the lives of over 300,000 children with cancer. That is why we support research at all stages, from basic science to advanced clinical trials, because every phase of research holds the potential to save children's lives.

CureSearch Research by the Numbers
2014 Year to Date

ACCELERATION INITIATIVE RESEARCH
$5 million committed over 3 years

New potential therapies tested on Ewing Sarcoma cells
Mary Beckerle, PhD
Huntsman Cancer Institute
at the University of Utah
$1.73 million
6-Month Progress Report

Compounds tested to inhibit medulloblastoma growth
William Weiss, MD, PhD
The Regents of the University of California, San Francisco
$1.88 million
6-Month Progress Report

Novel treatment for an upcoming Phase I clinical trial
Kathleen Sakamoto, MD, PhD
Stanford University
$1.37 million
6-Month Progress Report

YOUNG INVESTIGATORS
$1.2 million committed over 2 years

"Without organizations like CureSearch many of these exciting scientific endeavors would not be possible...In the not too distant future, through these supported efforts, we truly believe we can discover better therapies that will lead to the eradication of pediatric sarcomas and other childhood cancers."

–Dr. Jason Yustein, CureSearch Young Investigator and recent recipient of a $2 million research grant

SUPPORTING FAMILIES

CureSearch hosts events around the country to honor children and families and rally communities in the fight against children's cancer. CureSearch continues to provide education and resources so that no child faces a diagnosis and treatment without a fully equipped team behind them.


Webinars for family support
Podcasts about cancer research

Educational videos explain cancer treatments
Facts and figures

57 CureSearch Walks
4 CureSearch Ultimate Hikes in 34 states

412,000 unique visitors
28,500 participants

ACCELERATING RESEARCH

In order to build momentum toward a cure for all children's cancers, CureSearch is:

SUPPORTING CLINICAL TRIALS WITH $1.2 MILLION at 78 hospitals around the country

BUILDING THE PIPELINE of promising scientists studying children's cancer

15 SCIENTISTS

3 Acceleration Initiative Research Teams
12 Young Investigators

15 DISEASE AREAS

Affecting 15,700
children each year

One of our CureSearch Young Investigators, Dr. Alex Kentsis, explains his research on rhabdoid tumors, a rare and deadly form of childhood cancer.

ACCELERATING THE PACE OF TRIALS

patient studies developed by
CureSearch researchers

children enrolled in new trials
designed by CureSearch researchers

Acceleration Initiative Researcher Dr. Sakamoto discusses her upcoming Phase I clinical trial that uses an antibody therapy to treat children's tumors.

CURESEARCH FAMILIES

"At CureSearch, we are committed to changing the odds for children most at risk for losing their battle with cancer. We know that the 15,700 infants, children, and adolescents diagnosed with cancer each year deserve new and better treatments, faster than at a pace of 2 in 25 years. We're fighting for the future every child deserves and every parent dreams of."

- Laura Thrall, President and CEO of CureSearch for Children's Cancer

After being diagnosed with Wilms tumor at age 2, Luke Anderson underwent 5 hospitalizations during 10 rounds of chemotherapy and 12 days of radiation. Together with his family's strength and determination, Luke made it through treatment successfully and is now a proud cancer survivor and a healthy second grader.

Before her second birthday, Margo Miller was diagnosed with acute lymphocytic leukemia, the most common childhood cancer. During her second year of treatment, Margo's leukemia relapsed and became resistant to treatment. This spring, Margo began a novel immunotherapy treatment that uses her own immune system cells to fight her leukemia.

At CureSearch, we fight daily for Luke, for Margo, and for the families and communities that rally around them as they battle this devastating disease.

YOUR SUPPORT MAKES THE
DIFFERENCE

Your support helps make cures possible for children like Savannah.

And at every step of the way, we will be sharing our progress and our impact with you.

Your support allows us to continue:

Advancing RESEARCH
Supporting FAMILIES
Accelerating the SEARCH

CURESEARCH PARTNERS

Our work would not be possible without the generous support of thousands of CureSearch donors.

We are honored to recognize the following donors for their extraordinary support:

Nick Currey Fund
Support for the Acceleration Initiative,
"A Novel Epigenetic Strategy to Treat Ewing Sarcoma"
Genentech
Support for CureSearch Young Investigator,
Survivorship and Late Effects
Team Jack Foundation
Support for the Acceleration Initiative,
"Overcoming Resistance in High Risk Medulloblastoma"
sigma-tau
Support for CureSearch Young Investigator,
Adolescent and Young Adults
Hope Street Kids
Support for the Acceleration Initiative
Ronald McDonald House Charities
Support for Educational Resources
Amgen
Support for the Acceleration Initiative
Pfizer
Support for Educational Resources
Jacob Koenigs 'Jakefest' Memorial Fund and Kiewit
Support for the Acceleration Initiative
Support for CureSearch Young Investigator, Rhabdomyosarcoma