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Ewing Sarcoma in Children



About Ewing Sarcoma

Ewing sarcoma is the second most common bone cancer in children. It occurs most frequently in the long bones of the legs or arms, the pelvis, chest wall, spine and the skull, but can also begin in the soft tissues and not involve bone. This disease most often occurs in adolescents, with nearly half of cases arising between the ages of 10 and 20. Ewing sarcoma is somewhat more common in males than in females.

“The Ewing Family of Tumors” includes Ewing sarcoma, atypical Ewing sarcoma, and peripheral primitive neuroectodermal (PNET) of bone or soft tissue, and they are all treated in the same manner. A chromosomal mutation can be identified in the tumor cells of the Ewing Family of Tumors. The chromosomal mutation is not part of the genetic make-up of the person with the tumor, it is only in the tumor cells; the tumor is not inherited. The cause of the Ewing Family of Tumors is not yet known but it is believed this mutation plays an important role.

Signs and Symptoms of Ewing Sarcoma

The symptoms of depend on the bone or soft tissue site in which the cancer develops, but they usually include:

  • Pain at the site of the mass, often with swelling
  • Patients may have general symptoms such as loss of appetite, fever, malaise, fatigue, and weight loss
  • Other symptoms are related to the specific location of the tumor. Classic symptoms include chest pain and shortness of breath in tumors that originate in the ribs, and back pain and “sciatic–like” symptoms in patients with tumors in the pelvis.

News About Ewing Sarcoma

Ewing Sarcoma in Children was last modified: July 26th, 2016 by Geoff Duncan
Nick Currey Fund Advances Children’s Cancer Research

Nick Currey Fund Advances Children’s Cancer Research

In 2005, Nick Currey lost his life to Ewing sarcoma, a cancer of the bone (and at times, soft tissue). He was only 19 years old. His parents, Nancy and Ralph Currey, established the Nick Currey Fund in his memory to help fund new and improved therapies for Ewing... read more
$1.26M Awarded to Researcher Accelerating the  Search for Children’s Cancer Cures

$1.26M Awarded to Researcher Accelerating the Search for Children’s Cancer Cures

CureSearch for Children’s Cancer awarded a total of $1.26M to a leading pediatric cancer researcher for the Acceleration Initiative 3 Grand Challenge Award. Selected from 33 competitive applicants from the US and Canada, the winning research proposal will address critical challenges in pediatric cancer treatments and accelerate the discovery of clinical biomarkers to be used to inform diagnosis and treatment.

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Jake Beresh, Ewing Sarcoma

Jake Beresh, Ewing Sarcoma

6 Years Old at Diagnosis. Jake Beresh was diagnosed with Ewing sarcoma when he was six years old. As part of his treatment, he underwent surgery and chemotherapy. Now, at 19 years old, he is a sophomore at Nebraska Wesleyan University. We asked Jake a few questions... read more

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