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CureSearch for Children's Cancer - Support cures by donating now

CureSearch Ultimate Hike - Accelerating the pace to end children's cancer

We're changing the odds for the 42 children diagnosed with cancer each day.

Latest news and stories

Ultimate Hiker Frank Gioscia raises $500K for Childhood Cancer Research

Honoring Luke’s Legacy: Join Us This Childhood Cancer Awareness Month to Support Life-Saving Research

New Pediatric Cancer Clinical Trial at Washington University aims to Find Alternative to Standard Therapies

CureSearch and UK-based LifeArc to Co-fund Nearly $1.5M in High-grade Glioma Research

Dr. Lee’s Mission: A Promising Future for Children with Advanced Ewing Sarcoma

We focus on areas of unmet need

Every child deserves safe treatment.

We are dedicated to ensuring that every child diagnosed with cancer has a safe and effective treatment option. Focusing on pediatric cancers with insufficient or ineffective treatment options is a priority of our research strategy. Our unique funding strategy focuses on addressing areas of unmet need, including:

• Cancers with the lowest survival rates

• Limited or most damaging treatment options

• Populations that are underserved, including adolescents and young adults

Our unique funding strategy is delivering results

Our research funds groundbreaking, lifesaving breakthroughs.

CureSearch is armed with the best-in-class advisory councils that ensure research is engineered to advance to the marketplace. This accelerated research is quickly leading to new advancements, including:

• A novel drug for Ewing sarcoma in pediatric clinical trials

• A clinical trial for high-grade glioma that is now enrolling patients

• A new treatment for recurrent, refractory medulloblastoma in pediatric clinical trials

Our projects are 7x more likely to advance

Speed is critical, because children with cancer can't wait.

60% of preclinical research projects funded through our Acceleration Initiative advance to clinical trials, compared to a less than 8% average rate of translation for drugs into clinical cancer trial. CureSearch-funded pre-clinical projects are 7x more likely to advance to clinical trials and get there 1.5x faster compared to the national average.

We ONLY fund translational research

A "bench to bedside" focus is critical.

There is a significant funding gap for translational, preclinical, and early-phase clinical trials. CureSearch only funds translational research projects with the strongest potential to become a new treatment and quickly reach patients. In the last 5 years, we’ve awarded more than $12 million in research grants for projects dedicated to developing new therapies for kids with cancer.

Simply put, if a project isn't on an accelerated path to new drug development, we don’t fund it.

Your support changes the odds!

Our mission is to end children's cancer by driving targeted and innovative research with measurable results in an accelerated time frame. The research we fund is delivering safer, more effective children's cancer treatments. Thank you for your support!

CureSearch Impact Report 2023- preview image

Read the Impact Report

Get involved to end children's cancer

An unparalleled research strategy

Our Scientific and Industry Advisory Councils are comprised of experts at the top of their fields, and validation of a research project by our Scientific Review Committee speaks volumes in the global children's cancer arena.

Scientific Advisory Council

Led by Brenda Weigel, MD, MSc

The Scientific Advisory Council includes leading pediatric oncologists who set the academic priorities for CureSearch research initiatives and evaluate projects on scientific merit.

Dr Sallan and pediatric Patient Dario Deane (consent # 1419) in the JFC play room. For Paths of Progress FW 2007.

Scientific Review Committee

Led by Stephan Sallan, MD

The Scientific Review Committee provides rigourous peer review of research proposals, evaluating: scientific merits, innovation, unmet need and clinical impacts.

Industry Advisory Council

Led by Jeffrey Skolnik, MD

The Industry Advisory Council includes leaders from the largest global oncology and biotechnology companies who review potential research projects for clinical and regulatory feasibility.

Our Corporate Partners

The team at LESS+MORE generously offered their services pro bono in 2023 to design a stunning suite of refreshed Ultimate Hike creative. This rebrand reflects our commitment to prioritize the growth of Ultimate Hike as our largest annual fundraising campaign.

Through a partnership with Mattel, CureSearch is honored to provide Brave Barbies to childhood cancer patients. Hair loss is a common side effect of chemotherapy and radiation therapy treatments. Brave Barbie helps children better understand their hair loss and provides a "friend" through treatment and beyond.

"We’re proud to be a long-time partner of CureSearch with 10+ years of support for children’s cancer research. This relationship demonstrates to both the employees and customers of Iron Hill Brewery & Restaurant that we care deeply about the wider community that we serve. We know CureSearch is hard at work finding new treatment options for kids and together we are helping to put an end to childhood cancer."

Kevin Finn

Founder and President, Iron Hill Brewery & Restaurant

"Our annual Jakefest events honor the memory of my son, Jake, who passed away after a heroic fight with rhabdomyosarcoma. Kiewit has partnered with CureSearch because they're uniquely positioned to accelerate the pace of finding new drugs for kids. Through the generosity of Kiewit's employees, their spouses, friends, relatives, and our gracious business partners, over $3,000,000 has been raised for CureSearch. We could hardly have imagined twelve years ago the outpouring of goodwill this event has brought."

Harry Koenigs, Jake's Dad

Area Manager, Kiewit

“Busy Bee is proud to be a sponsor for CureSearch! It’s our privilege to support such an incredible organization that’s work, mission and drive will benefit ALL of us. We are thankful for the brilliant and hardworking teams that work tirelessly to end childhood cancer!”

Elizabeth Waring

President, Busy Bee

“As a leading clinical research organization, Parexel is committed to making a difference in patients’ lives and collaborating with organizations who also keep the patient at the heart of everything they do. Parexel is delighted to sponsor CureSearch’s National Walk and join this important effort to provide research funding to find new safe and effective treatments for children with cancer.”

Katherine Minson

Senior Medical Director, Parexel