Acceleration Initiative – An Outcome Driven Approach

Our Acceleration Initiative projects are highly innovative, address a significant challenge in pediatric cancer drug development, and have a strong probability of clinical application — ready to reach patients within three to five years. To learn more about applying for one of our grants, click here.

ACCELERATION INITIATIVE – ACTIVE PROJECTS

Gregory Friedman, MD
University of Alabama at Birmingham
Focus: Pediatric High-Grade Glioma 
Project title: Overcoming the Adverse Microenvironment of Pediatric High-Grade Gliomas

David Langenau, PhD
Massachusetts General Hospital 
Focus: Rhabdomyosarcoma
Project Title:Targeting p53 in childhood rhabdomyosarcoma

Andrei Thomas-Tikhonenko, PhD
Children’s Hospital of Philadelphia 
Focus: High-risk Pediatric Cancers – Neuroblastoma and Diffuse Midline Glioma 
Project title: Targeting splicing-derived neo-epitopes in high-risk pediatric cancers

Andrew Kung, MD, PhD
Memorial Sloan Kettering Cancer Center
Focus: Pediatric Sarcoma
Project Title: Integrative analysis to identify new therapies for pediatric sarcoma

Frequently Asked Questions

ACCELERATION INITIATIVE - COMPLETED PROJECTS

Mary Beckerle, PhD
Ewing Sarcoma

William Weiss, MD, PhD
Medulloblastoma

Richard Gilbertson, MD, PhD
Brain Cancer

Maria-Grazia Roncarolo, MD
Acute Myeloid Leukemia (AML)

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